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Appendix B : Supplementary Information for Reference Toxicity Data

By Environmental Protection Agency

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Book Id: WPLBN0000022884
Format Type: PDF eBook
File Size: 0.3 MB
Reproduction Date: 2007
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Title: Appendix B : Supplementary Information for Reference Toxicity Data  
Author: Environmental Protection Agency
Language: English
Subject: Ecology, Natural resource issues, Environemtal protection
Collections: Environmental Awareness Library Collection
Publication Date:
Publisher: United States Environmental Protection Agency


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Agency, E. P. (n.d.). Appendix B : Supplementary Information for Reference Toxicity Data. Retrieved from

Excerpt: SUPPLEMENTARY INFORMATION FOR REFERENCE TOXICITY DATA Appendix B contains technical and explanatory notes, and supplementary tables pertaining to the statistical analyses of reference toxicant test results presented in Chapters 3 and 5. B.1 Acquisition, Selection, and Quality Assurance of Data Details of data quality assurance and test acceptance are provided in a separate document, available from the EPA Office of Water’s Office of Science and Technology (“Whole Effluent Toxicity (WET) Data Test Acceptance and Quality Assurance Protocol”). On request, EPA will also make available a list by laboratory of quality assurance (QA) flags, test dates, toxicant concentration, and summary statistics for the NOEC, EC25, and EC50 estimates and the test endpoints (survival, growth, reproduction, etc.). Laboratories are not named. Data were obtained as data sets from the data base and statistical software packages TOXIS® and TOXCALC® (see Chapter 8 for citations). TOXIS® software produces an acceptability criterion field code based on the TAC specified by the EPA WET test methods. The tests having “I” (Incomplete) or “F” (Failed) values in this field were eliminated from consideration. TOXCALC® data were examined at the individual test level. The first step, before data entry, consisted of examining the test for TAC from bench sheets. The data were then imported into TOXCALC® for analysis. However, TOXCALC®, unlike TOXIS®, does not generate error codes but issues a warning on the screen. These messages were examined and decisions were made case-by-case following EPA test methods. In the second step, a QA program code was written in SAS® to check the TAC listed in the WET test methods for acute and chronic toxicity tests.

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